What is the first line treatment for Intertrigo caused by candidiasis?

Topical treatment with Nystatin or azoles, combined with measures to keep the affected area dry, is considered the first-line treatment for intertrigo caused by candidiasis. Intertrigo is a skin condition that occurs in moist areas of the body, where friction and moisture promote fungal growth, particularly from Candida species.

Using topical antifungals like Nystatin or azoles targets the underlying fungal infection directly at the site, providing localized treatment that is both effective and minimizes systemic side effects. Keeping the area dry is crucial in managing intertrigo, as moisture creates an environment in which Candida thrives, potentially exacerbating the condition. Therefore, a combination of topical antifungal therapy and proper hygiene measures creates a synergistic effect that helps resolve the infection and promote healing.

Other options, while they may be effective in certain scenarios, are not the first line for such localized infections. For instance, IV Echinocandins and oral Fluconazole are more appropriate in systemic infections or severe cases where systemic treatment is warranted. Clotrimazole troches are typically used for oral thrush rather than skin infections.