For patient-applied treatment of Genital Warts (HPV), what is the recommended first line treatment?

The recommended first-line treatment for patient-applied treatment of genital warts (caused by HPV) is Imiquimod cream. Imiquimod is a topical immune response modifier that works by stimulating the immune system to target and eliminate the HPV-infected cells. It is well-suited for self-administration, making it convenient for patients. Patients apply the cream themselves, typically three times a week for up to 16 weeks, which allows for ongoing management while providing the patient with a sense of control over their treatment.

Podophyllin, while used in some treatment regimens, is not recommended for patient-applied use due to the need for a healthcare professional to supervise its application. Cryotherapy is a provider-administered procedure that involves freezing the warts and is not suitable for patient use. Trichloroacetic acid is also applied by a healthcare professional and does not allow for self-treatment. Therefore, Imiquimod cream stands out as the most effective and practical option for patients managing genital warts on their own.